The SeraSpot MicroArray assay for the detection of antibodies to Borrelia burgdorferi is performed by ArminLabs.
The SeraSpot MicroArray assay combines standardized and reliable microtitrator plate and microarray technology in a single micro well. Parameters include the presence of Borrelia burgdorferi antigens printed at the nanoliter scale on the bottom of the microtiter plate wells.
SeraSpot has higher sensitivity and specificity for detection of Borrelia burgdorferi antibodies compared to ELISA and test immunofluorescence methodology
SeraSpot MicroArray for the detection of antibodies to Borrelia burgdorferi is a confirmatory test in the serodiagnosis of borreliosis and analyzes IgG/IgM antibodies to the following Borrelia burgdorferi proteins and subspecies
VlsE (B.b. afzelii), p39 (B.b. afzelii), p39 (B.b. afzelii), p58 (B.b. garinii), p100 (B.b. afzelii), OspC (B.b. afzelii + B.b. garinii + B.b. sensu stricto), DbpA (B.b. afzelii + B.b. garinii + B.b. sensu stricto).
However, it is known that the production of specific antibodies to Borrelia burgdorferi proteins can be impaired in some cases. To diagnose the level of specific cellular immunity to Borrelia burgdorferi there is a modern highly sensitive immunological assay
